DEPARTMENT OF DERMATOLOGY UNIT-I

The Department of Dermatology was founded by Professor Syed Ghulam Shabbir in 1960. The present building was completed in 1970 and it comprised of 56-bedded in-patient, out-patient block and a laboratory.

Professor Tahir Saeed Haroon joined the department in 1989 and elevated it to a real state of the art center over the years. Though photochemotherapy unit had been already working since 1986, patch test clinic, immunofluorescence facility, laser unit and dermatosurgery theatre were added in the department during his tenure. After his retirement, Professor Dr. Sabrina Suhail Pal took over the charge in 2002. The Teledermatology unit was established in 2003.

In June, 2004 the department was converted into unit I and II, currently being headed by Prof. Dr. Ijaz Hussain and Prof. Dr. Tahir Jamil Ahmad, respectively.

The Department of Dermatology is a centre of excellence which serves as a referral centre for patients from all over the country. Patients are referred for patch test, phototherapy, vitiligo surgery, punch grafting, dermabrasion, cryotherapy, laser therapy and laboratory investigations like dermatohistopathology, immunofluorescence and mycology. It has a busy out-patient with a turnover of about 100,000 patients per annum (heaviest in the hospital) and its 56-bedded in-patient ward along with intensive care units. The department has a well-maintained library, audiovisual section, computer section and a well-appointed auditorium with a seating capacity of 60 persons.

The department is actively involved in teaching undergraduate and postgraduate medical students, nurses and general practitioners.

• To provides best educational and clinical facilities in the department.
• To provide facilities, for the research work

LIST OF TEACHING PROGRAMS

Undergraduate Teaching:

1. MBBS

Postgraduate Training:

1. FCPS (Fellow of College of Physicians and Surgeons Pakistan)
2. MD (Doctorate in Medicine)
3. MCPS (Member of College of Physicians and Surgeons Pakistan)
4. Dip Derm (Diploma in dermatology)

COURSES:

1. Family Physicians
2. Nurses
3. Dispensers

TEACHING AIDS:

Our library is one of the largest departmental libraries having more than 1000 books on different aspects of dermatology. There is a regular inflow of major national and international journals of dermatology. The department is also equipped with latest computer section with desktop computers, laptops and internet facilities. The audiovisual section has different still cameras, digital cameras, overhead projector, slide projectors, and multimedia projector.

SERVICES

Laboratory:

The laboratory is furnished with routine and special investigative equipment. Following sections are part of our laboratory:

1. Dermatopathology
2. Immunofluorescence
3. Mycology

Besides routine blood and urine tests, following specialized tests are also performed:

1. Blood Sugar
2. Porphyrin detection By Wood’s Lamp
3. Smears for acid-fast bacilli, Leishman-Donovan bodies
4. Tzanck smear
5. Scraping For Mite
6. Scraping For Fungus
7. Slide for Malarial Parasite

Phototherapy:

The department was pioneer to install phototherapy unit in the country in January 1986. This section consists of ultraviolet-A and ultraviolet-B whole body radiation chambers and local lamps. In 2009 phototherapy unit was further upgraded with the addition of narrowband UVB. This mode of treatment is successful for a number of common and rare dermatoses.

Patch Test:

This department was the first to introduce patch testing which is a unique procedure to diagnose allergic contact dermatitis. European standard series and shoe series are usually used.

Laser Therapy:

Dermatology Department, Mayo Hospital took lead to introduce laser (Nd:YAG) therapy in public sector hospitals for the first time in Pakistan in the year 1995. Later intense pulsed light was added in our laser unit in 2009. This is being used for hirsutism, pigmentary disorders and acne. These services are available free of charge.

Fractional CO2 laser was added to the unit in July 2013 for treatment of acne scars and skin rejuvenation.

Teledermatology:

Teledermatology section was setup in the year 2003. It is useful both for the patient management and academic purposes. We respond to queries regarding skin diseases or their management put forwarded to us.

In collaboration with telemedicine unit at Mayo Hospital, one of our consultants has weekly session, where patients from four different cities are evaluated.

Dermatosurgery:

Procedures for diagnostic, therapeutic and cosmetic purposes are regularly carried out in the theatre.

The unit has always been a hub of research activities. Presentations are made at national and international forums. Publications of our research in national and international journals are a regular feature.

PUBLISHED RESEARCH WORK:

• Hussain I, Rani Z, Rashid T, Haroon TS. Suitability of European Standard Series allergens in Pakistani patients with allergic contact dermatitis. Contact Dermatitis 2002; 46: 50-1.
• Rani Z, Hussain I, Haroon TS. Common allergens in shoe dermatitis. Our experience. Int J Dermatol 2003; 42: 605-7.
• Rani Z, Haroon TS. Management of atopic dermatitis: An update. J Pak Assoc Dermatol 1998; 8: 18-20.
• Hussain I, Rehman FU, Rani Z, Haroon TS. Antibiogram in community-acquired skin and subcutaneous infections due to Staphylococcus aureus. Ann KEMC 2000; 6: 249-50.
• Hussain I, Rani Z, Rashid T. Dyshidrosiform bullous pemphigoid . A case report and review of literature. J Pak Assoc Dermatol 2001; 11 (1): 69-71.
• Rani Z, Rashid T, Hussain I. Clinical profile in 350 patients with contact dermatitis. J Pak Assoc Dermatol 2001; 11 (2): 3-6.
• Rani Z, Hussain I, Haider M. An unusual case of progressive symmetric erythrokeratoderma with unreported features. J Pak Assoc Dermatol 2001; 11 (4): 43-7.
• Rani Z, Hussain I, Haroon TS. Allergic contact dermatitis: a comparison between atopic and non-atopic individuals. J Coll Physicians Surg Pak 2002; 12: 40-42.
• Rani Z, Hussain I. Teledermatology: Future prospects in our scenario. (editorial). J Pak Assoc Dermatol 2002; 12 (1): 1-2.
• Rani Z, Hussain I, Nadeem M, Haroon TS. Nickel dermatitis: clinical patterns and patch test reactivity. Our experience. J Pak Assoc Dermatol 2002; 12 (1): 10-14.
• Muzaffar F, Hussain I, Rani Z. Emollients as an adjunct therapy to topical corticosteroids in children with mild to moderate atopic dermatitis. J Pak Assoc Dermatol 2002; 12: 64-8.
• Rani Z, Ahmad ML, Hussain I, Haroon TS. Clinicoetiologic correlation in 121patients with hand eczema. Medical Channel 2002; 8 (3): 14-17.
• Rani Z, Hussain I, Ahmad TJ. Allergy to para-tertiary-butylphenol formaldehyde resin in general population: A retrospective analysis of 37 cases. J Pak Assoc Dermatol 2002; 12: 171-4.
• Rani Z, Ahmad ML, Hussain I et al. A 7-year girl with photosensitivity and neurological abnormalities. Cockayne’s syndrome or De Sanctis-Cacchione syndrome? A diagnostic dilemma. J Pak Assoc Dermatol 2002; 12: 206-10.
• Rani Z, Hussain I. Immunofluorescence in immunobullous diseases. Pak Assoc Dermatol 2003; 13: 76-88.
• Rani Z, Rashid T, Hussain I. Erythema annulare centrifugum in association with hypothyroidism: a case report. Pak Assoc Dermatol 2003; 13: 89-91.
• Rani Z, Ahmad TJ, Hussain I. Vohwinkel’s syndrome: case report and review of literature. Pak Assoc Dermatol 2003; 13: 92-5.
• Rani Z. Vitiligo: from Babechi to lasers. J Pak Assoc Dermatol 2003; 13: 112-3.
• Ahmad TJ, Rashid T, Rani Z, Haroon TS. Autologous skin punch grafting in localized, fixed vitiligo. J Pak Assoc Dermatol 2003; 13: 114-6.
• Ahmad TJ, Rashid T, Rani Z. Modifications in punch grafting. J Pak Assoc Dermatol 2003; 13: 146-7.
• Kamal T, Rani Z, Haroon TS, Hussain I. Comparative efficacy of topical calcipotriol ointment with betamethasone valerate ointment in chronic plaque psoriasis. J Pak Assoc Dermatol 2004; 14: 16-22.
• Nabi H, Rani Z, Shahzad A, Netherton’s Syndrome: A case report. J Pak Assoc Dermatol 2004; 14: 96-100.
• Khan MS, Rani Z, Ahmed ML, Hussain I, Kazmi AH. Evaluation and pattern of nickel dermatitis in patients with allergic contact dermatitis. Pak Assoc Dermatol 2004; 15: 136-9.
• Nadeem M, Rani Z, Aman S, Kazmi AH, Shabbir A. Parthenium weed: A growing concern in Pakistan. J Pak Assoc Dermatol 2005; 15: 4-8.
• Rani Z, Khan MS Aman S et al. Quality of life issues and new benchmarks in the assessment of skin diseases. J Pak Assoc Dermatol 2005; 15: 340-5.
• Hameed A, Rani Z, Kazmi AH. Vitiligo: new etiology-based treatments. J Pak Assoc Dermatol 2005; 15: 252-61.
• Rani Z, Khan MS, Hameed A, Hussain I, Kazmi AH. Bone mineral density in patients with pemphigus vulgaris on steroid therapy. J Pak Assoc Dermatol 2006; 16: 10-3.
• Rani Z. Leprosy elimination strategy. J Pak Assoc Dermatol 2007; 17: 1-3.
• Rani Z, Kazmi AH, Sheikh RA, Rashid A, Waseem J, Raza A. Efficacy, safety and tolerability of mometasone furoate 0.1% in chronic eczema. J Pak Assoc Dermatol 2007; 17: 21-27.
• Rani Z, Kazmi AH, Mahmood K, Mahmood S, Aashiq Z. To study the local variations in the frequency and pattern of dermatoses in amputees in earthquake affected areas with recommendations to improve their quality of life. Pak J Med Res 2008; 47: 11-13.
• Ahmad TJ, Rashid T, Rani Z, Needling: an adjunct to narrowband ultraviolet B therapy in localized fixed vitiligo. J Pak Assoc Dermatol 2008; 18: 149-153.
• Asad F, Hameed S, Khurshid K, Bashir B, Rani Z, Pal SS. Efficacy and safety of intense plus light in idiopathic hirsutism. Annals of KEMU 2010; 16(1): 24-6.
• Rani Z, Tufail F, Asad F, et al. Frequency of allergic contact dermatitis in patients with chronic eczema. Annals of KEMU 2010; 16(1): 55-8.
• Khurshid K, Ullah I, Rani Z, Asad F, Aslam S, Pal SS. Efficacy and safety of narrow band UVB in treatment of chronic plaque psoriasis. Annals of KEMU 2010; 16(1): 31-3.
• Aslam S, Rani Z. Newer trends in skin rejuvenation. J Pak Assoc Dermatol 2012; 22:1-3. .
• Butt G, Khurshid K, Rani Z, Asad F, Pal SS. Frequency of pulmonary tuberculosis in patients with skin diseases requiring high dose long-term systemic steroid therapy. J Pak Assoc Dermatol 2013; 23: 126-132.
• Sarwar U, Asad F, Khurshid K, Rani Z, Pal SS. Frequency of allergic contact dermatitis in hand eczema patients with European standard and corticosteroid series. J Pak Assoc Dermatol 2013; 23:289-294.
• Bashir B, Asad F, Khurshid K, Rani Z, Pal SS. Comparison of hair reduction in idiopathic hirsutism by intense pulsed light at two different wavelengths in
• Asian skin types. J Pak Assoc Dermatol 2013;23:418-422.
• Saeed W, Asad F, Khurshid K, Rani Z, Pal SS. Efficacy of intense pulsed light in melasma. J Pak Assoc Dermatol 2014;24:212-216.
• Tufail F, Asad F, Khurshid K, Rani Z, Pal SS. Common allergens in patients of chronic eczema by patch testing with European standard series. J Pak Assoc Dermatol 2014;24:302-306.
• Butt G, Bano S, Pal SS, Khurshid K, Asad F, Rani Z, Neutral lipid storage disease-a case report. J Pak Assoc Dermatol 2014; 24: 176-179.
• Butt G, Asad F, Rani Z, Hussain I. Pulmonary tuberculosis in dermatological patients on high-dose, long-term steroid therapy. J Pak Assoc Dermatol 2015;25:1191-131.
• Asad F, Haroon TS, Hussain I. Side effects of cyclosporin therapy. J Pak Assoc Dermatol 1999; 9: 20-4.
• Pal SS, Haroon TS, Asad F, et al. Efficacy and safety of intermittent short courses of cyclosporin (microemulsion form) in chronic plaque psoriasis. Pak PG Med J 1999; 10: 69-73.
• Pal SS, Zaman T, Asad F, et al. Effects of treatment on quality of life in patients with chronic plaque psoriasis. Pak PG Med J 1999; 10: 84-7.
• Asad F, Qadir A, Nadeem M. Quality of life in patients with acne vulgaris. CPSP (2002).
• Asad F, Haroon TS. Depression and skin (editorial). Pak J Med Sci 2002;18:31-5
• Sabrina Suhail Pal, Asad F, Khurshid K, Haroon TS. Significance of Single Vs multiple skin biopsies. Annals OF King Edward Medical College 2002;8:108-10.
• Pal SS, Asad F, Khurshid K, Haroon TS. Correlation between clinical diagnoses and histopathological results in skin diseases: A study of 525 cases. J Pak Assoc Dermatol 2002; 12:73-6.
• Asad F, Qadir A, Ahmad L. Anxiety and depression in patients with acne vulgaris. J Pak Assoc Dermatol 2002; 12:68-71.
• Asad F, Pal SS. Quiza An erythematous nodule on outer aspect of arm in a female with breast carcinoma. J Pak Assoc Dermatol 2003;13:97.
• Asad F, Pal SS. Quiza An erythematous plaque on breast. J Pak Assoc Dermatol 2003;13:157
• Asad F, Pal SS, Dermatofibroma sarcoma protuberens case report. J Pak Assoc Dermatol 2002; 12:106-9.
• Asad F, Pal SS, Leukemia cutis: an indicator of relapse in a patient with myeloid leukemia a case report. J Pak Assoc Dermatol 2005;14:259-61
• Asad F, Haroon Nabi, Muhammad Nadeem. Narrowband ultraviolet B radiation therapy for vitiligo in Asians. J Pak Assoc Dermatol 2005; 15:146-50.
• Asad F, Pal SS. Quiz An annualar erythematous plaque on dorsum of hand. J Pak Assoc Dermatol 2004; 14:45-6.
• Asad F, Sabrina Suhail Pal, Leukemia cutis: an indicator of relapse in a patient with myeloid leukemia a case report. J Pak Assoc Dermatol 2005; 14:259-61.
• Shamsuddin S, Asad F, Nadeem M, Nabi H. Efficacy and safety of narrow band ultraviolet B therapy in psoriasis in Asian skin. J Pak Asso Dermatol. 2006; 16: 210-14
• Asad F, Sabrina Suhail Pal, Leukemia cutis: an indicator of relapse in a patient with myeloid leukemia a case report. J Pak Assoc Dermatol 2005; 14:259-61
• Asalm R, Qadir A, Asad F, Psychiatric morbidity in dermatological out patient : an issue to be recognized J Pak Asso Dermatol 2007; 17: 235-239
• Shansuddin S, Asad F, Nadeem M, Nabi H. Efficacy and safety of narrow band ultraviolet B therapy in psoriasis in Asian skin. J Pak Asso Dermatol. 2006; 16: 210-14
• Asad F, Naqqash S, Sabrina Suhail Pal, Shahzadi N, Hasnain A, Qadir A, Bari IU. Pattern of dermatoses and underlying psychological disorders in patients attending dermatological clinic in earthquake affected areas of Azad Kashmir. Pakistan Journal of Medical Research 2008; 47(1): 7-10.
• Asad F, Din S, Mohammed N. Lymphodema: another aspect in cutaneous lieshmaniasis J Pak Asso Dermatol 2010;19(4):.208-212
• Asad F, Hameed S, Khurshid K et al. Efficacy and safety of intense plus light in idiopathic hirsutism. ANNALS 2010;16(1):24-6
• Rani Z, Tufail F, Asad F et al. Frequency of allergic contact dermatitis in patients with chronic eczema. ANNALS 2010;16(1): 55-8
• Khurshid K, Ullah I, Asad F. Efficacy and safety of narrow band UVB in treatment of chronic plaque psoriasis. ANNALS 2010;16(1): 31-3
• Rani Z, Tufail F, Asad F, Khurshid K, Sarwar U, Sabrina Suhail Pal. Frequency of allergic contact dermatitis in patients with chronic eczema. ANNALS of King Edward Medical University 2010; 16: 55-8.
• Naqqash S, Asad F, Sabrina Suhail Pal. Efficacy and safety of azathioprine in the treatment of chronic actinic dermatitis. J Pak Assoc Derm 2010; 20: 222-6.
• Naqqash S, Asad F, Sabrina Suhail Pal. Direct immunofluorescence and histopathology in chronic discoid lupus erythematosus. J Pak Assoc Derm 2011; 21: 98-101.
• Sarwar U, Asad F, Rani Z, Khurshid K, Sabrina Suhail Pal. Frequency of allaergic contact dermatitis in hand eczema patients with European standard and corticosteroid series. J Pak Assoc Derm 2013; 23: 289-294.
• Aslam S, Khurshid K, Asad F, Rani Z, Sabrina Suhail Pal. Efficacy and safety of simvastatin in chronic plaque psoriasis. J Pak Assoc Derm 2013; 23: 310-14.
• Bashir B, Rani Z, Altaf F, Khurshid K, Sabrina Suhail Pal. Comparison of hair reduction in idiopathic hirsutism by intense pulsed light at two different wavelengths in Asian skin types. J Pak Assoc Derm 2013; 23: 418-22.
• Shaukat S, Aman S, Hussain I, Kazmi A.H. The effect of oral doxycycline and topical 5% benzoyl peroxide on quality of life in patients with mild to moderate acne vulgaris. J Pak Assoc Derma 2013;23(2):173-179.
• Batool S, Hussain I. Diogenes syndrome in a patient suffering from neurodegenerative disease. J Pak Assoc Derma 2015;25(3):220-222.
• Sagheer A, Shehzad A, Hussain I. Comparison of efficacy of intralesional 5- fluorouracil alone versus intralesional triamcinolone acetonide with 5-fluorouracil in small keloids. J Pak Assoc Derma 2016;26(4):361-365.
• Kashif M, Tahir R, Hussain I. Efficacy and safety of tricholoroacetic acid 35% versus adapalene 0.1% in treatment of molluscum contagiosum in children. J Pak Assoc Derma 2016; 26 (4):366-370.
• Kumar P, Hussain I. Leprosy in 21st J Pak Assoc Derma 2016;26(2):93-95.
• Iftikhar U, Hussain I. Telederematology: Examination the future. J Pak Assoc Derma 2016; 26(3):175-176.
• Khan S, Hussain I. IL-17 and its role in psoriasis. J Pak Assoc Derma 2017;27(1)1-3.
• Rana M, Altaf F, Bashir B, Rani Z. Frequency of associated factors of onychomycosis. J Pak Assoc Derma 2017; 27(3):226-231.
• Butt G, Hameed F, Bashir B, Hussain I. Generalized asymptomatic skin-coloured popular eruption. J Assoc Derma 2017; 27(3):306-308.

CURRENT RESEARCH WORK:

• Comparison of effectiveness of platelet rich plasma with fractional CO2 laser versus Fractional CO2 laser alone in treatment of acne scars.
• Comparison of efficacy and safety of topical tacrolimus 0.1% ointment vs topical triamcinolone acetonide 0.1% ointment in oral lichen planus
• Comparison of efficacy and safety of topical 4% hydroquinone vs. combination of topical 10% glutathione plus 5% ascorbic acid cream in patients of epidermal melasma
• Comparison of tacrolimus vs. cacipotriol in alopecia areata
• Comparison of association of anti TPO antibodies in patients of vitiligo and control group
• Efficacy of CO2 Fractional laser in moderate to severe acne scarring
• Frequency of autoimmune thyroid disorders in patients of pemphigus vulgaris
• Comparison between efficacy of 5% topical trans examic acid versus 2% topical Hydroquinone cream in patients of melasma
• Comparison between efficacy of 40% TCA & cryotherapy in platal warts
• To evaluate the efficacy of 10% zinc sulphate solution approved in the treatment of plane warts
• Association of early onset male androgenetic alopecia and metabolic syndrome
• Comparison of fractional Co2 Laser and 70% Tricholoroacetic acid peel in the treatment of facial freckles and lentiginous
• Comparison of serum prolactin level between healthy and psoriatic patients
• Comparison of 10% KOH and cryotherapy in treatment of MCs
• pylori seropositivity in children with atopic dermatitis
• Antioixdant status of serum Albumin, uric acid and bilirubin in pemphigus vulgaris
• Comparison of efficacy & safety ofg autologous PRP with fractional CO2 Laser vs fractional Co2 Laser alone in treatment of Mod. to severe acne scars: A split face study
• To determine serum cortisol levels I patients with atopic dermatitis

Efficacy of fractional CO2 laser vs 10% glycolic acid +0.05% tretnoin cream in ther treatment of striae alba

• Efficient outpatient management of the department run by qualified consultants.
• Skilled staff for clinical and operative procedure in the operation theater , Laser room, Laboratory and Dermatosurgery.

State of the art indoor management of the admitted patients with well-equipped team of paramedic staff and competent consultant & doctors

Two Ph.D scholars Dr. Ghazala Butt (MD) and Dr. Bushra Bashir (FCPS) are doing there Ph.D projects on stem cells in the department

Ph.D Projects

1. Adipose Tissue Derived Stem Cell Based Hair Restoration Therapy for Androgenetic Alopecia
2. Hypoxic Preconditioning of Aged Mesenchymal Stem Cells to Enhance their Skin Rejuvenation Potential